Ask Ausiello - Spoilers :

Question: One Tree Hill scoop demanded. Let’s be real. Will Lucas and Peyton ever return to Tree Hill? —Taylor

Ausiello: If this turns out to be the soap’s final season, I’d say there’s an 80 percent chance both will be back in the series finale.

Question: Why is it that there is still no juicy spoilerific scoop on One Tree Hill‘s new season? —Johnny

Ausiello: Um…. did you not see my spoiler last week about three longtime series regulars being killed off in the season premiere? You’re looking for something bigger than that? Okay, here it goes: Look for Victoria and Millicent to jeopardize the future of Brooks company. (BTW, that first part about the three series regulars getting whacked was a joke. It’s okay to laugh.)

Via : http://ausiellofiles.ew.com/2010/07/22/ask-ausiello-spoilers-greys-smallville-castle/